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Optical Rotation

Optical Rotation is measured on a Perkin Elmer 341 Polarimeter. This high-resolution instrument has an accuracy of ±0.0020. The rotation can be measured at 5 wavelengths, 589nm, 578nm, 546nm, 436nm and 365nm and the Polarimeter cell is temperature controlled with a Peltier unit, normally operated at 25°C.
Important applications include:
  • Characterisation of newly synthesised compounds
  • Quality control, especially of pharmacological substances which may depend on their enantiomeric purity


    •  We are able to offer a fast service for specific rotation. Use of an ultra micro balance combined with a 100mm micro cell allows accurate measurement with only 2ml of solution.

    Sample Requirements:   Typically 2-30mg per analysis.
    Other Requirements:      Required concentration, solvent and temperature.


    For quickest response, please download
    and send us an Analytical Data Form
    with each sample.

    >> Analytical Data Form (WORD Format)
    >> Analytical Data Form (Adobe PDF Format)

    © Exeter Analytical (UK) Ltd 2008